I've been using Renova every night, and I'm on my 4th month of using. I think I apply more than the instructions suggest, because I'd say the size of my drop of cream is more like 2 averages peas, or a small grape. I've had no reactions or irritation, and I haven't seen any difference in my skin. I know it takes a long time to see results, if they're ever seen, but my Renova brochure says that that lightening of pigmentation may be seen after using Renova for 3-4 months. At times, my pigmentation seems worse...but I use SPF30PA++ everyday, and I use SPF20 mineral powder over everything...
Has anyone here tried Refissa? I'm wondering if the higher concentration of tretinoin may be worth a try.